Rebuild, Rewire, Resurrect
From intuitive AI to de-extinct wolves. This week’s signals show how we’re reengineering health, systems, biology, and care.
Between resurrected wolves and mood-sensing AI, the lines between biology, tech, and everyday wellness are dissolving.
What used to feel experimental is now being productized.
What used to be elite is starting to scale.
What was reactive is becoming precision-based and preventive.
Here are some of the most interesting signals shaping the future of longevity, healthspan, and performance this week:
Latest Launches
Timeline Dropped an Eye Cream Product
OneSkin Expanded Into Scalp Health
ElevenLabs’ Conversational AI is now HIPAA-Compliant
This Week’s Rundown
From Reactive To Intuitive AI — Anastasia Georgievskaya
Longevity Is A Full-Scale Economic Shift — Dr. Marta Ra
Longevity Clinics Are Scaling, But Missing the Foundation — Gari Zmudze
Gyms Are Quietly Becoming Longevity Clinics — Delphine Le Grand
The Dire Wolf Is Back: What De-Extinction Means for Human Longevity
Must Reads + Listens
Optimizing Human Health — Dr. Fady Hannah-Shmouni
Want to stay young? Survive the next 10 years — Peter Diamandis
Latest Launches: New Tools for the Long Game
Timeline’s Eye Cream
Timeline dropped a new product:
→ Eye Cream with Urolithin A to target cellular aging around the eyes at the mitochondrial level.
💡 Why it matters: Mitochondrial health is quietly becoming the front line of anti-aging. This is biotech wrapped in skincare.
👀Just a heads-up: Timeline has another first-of-its-kind product dropping on April 14 — Stay tuned.
View New Product →
Use code: BIOCOMPASS for 10% off!
**UPDATE
Timeline’s Mitopure Gummies Have Arrived!
→ A new way to slow muscle loss with age. Urolithin A gummies work at the cellular level.
💡 Why it matters: We lose up to 8% of muscle per decade after 30. Timeline’s tackling it from the mitochondria up.
Try the new Mitopure Gummies for FREE. While supplies last! →
OneSkin’s OS-01 HAIR Serum
OneSkin expanded into scalp health with a peptide serum that targets cellular senescence at the follicle level.
📈 76% saw new hair growth in 3 months.
💡 Skin and hair aren’t cosmetic anymore, they’re therapeutic surfaces.
Aging isn’t just about skin, your scalp ages too. And OneSkin is treating it like a living organ.
ElevenLabs’ HIPAA-Compliant Conversational AI
Eleven Labs just announced their conversational AI is now safe for healthcare use, meaning it can securely handle reminders, notes, coaching, documentation, and patient interaction.
💡This is huge. If AI is going to scale in healthcare, it needs trust and privacy baked in, and ElevenLabs just took a big step in that direction.
This Week’s Rundown:
🧠 From Reactive to Intuitive AI
Anastasia Georgievskaya — Haut.AI
In her recent Forbes feature, Anastasia explores the rise of intuitive AI as a technology that can interpret micro-expressions, tone of voice, and emotional states in real time.
It’s already being used in skin diagnostics.
But the implications go far beyond skincare, into mental health, wellness, and how we interact with healthcare itself.
💡 Why it matters:
We’re moving from prompt-based tools to systems that sense us.
Skin, tone of voice, and emotional patterns are becoming real-time inputs for personalized care.
As AI becomes more human, it won’t just respond.
It will anticipate, and quietly reshape how we experience health support.
💳 Longevity is one of the most consequential economic and societal transformations of our time
Dr. Marta Ra, in conversation with Julius Baer, reframes longevity as a societal redesign, not a wellness trend.
Just like climate or AI, longevity is a macroeconomic force. This isn’t just about living longer. It’s a full-scale economic shift, a redesign of how we live, work, invest, insure and age.
Healthspan > Lifespan
Aging = Economic Pressure + Opportunity
Women = Driving Health + Wealth Decisions
Access = The Great Divider (or Multiplier)
💡Why it matters:
→ This is about systemic redesign, not just supplements.
→ The 100-year life needs a new operating system.
🔬 Longevity Clinics Are Scaling — But Missing the Foundation
via Gari Zmudze | Longevity Clinics Survey 2025
There’s momentum in the clinic space, but cracks are showing.
According to the Longevity Clinics Survey 2025:
The good news:
Clinics are adopting advanced diagnostics
Wearables and biological age testing are becoming standard
Demand is rising fast, specially from Gen X
The gaps:
77% plan to expand, but only 39% are profitable
There’s no standardized training for longevity doctors
Many skip core diagnostics like cognition, hearing, and oral health
💡 Gari Zmudze’s take:
The future isn’t more clinics. It’s smarter infrastructure:
→ Centralized expertise + distributed, at-home diagnostics
→ Monthly biomarker tracking
→ Seamless digital coordination
This is concierge care, but built to scale, not just for the elite.
Because longevity’s real challenge isn’t science.
It’s systems.
🏃🏽♀️ Gyms Are Quietly Becoming Longevity Clinics
Equinox, Life Time, Love.Life, Remedy Place, and THE WELL, are blurring the line between fitness and medicine, offering diagnostics, recovery, coaching, even IV therapy.
Why it matters:
Gyms have what clinics lack: habit, frequency, motivation.
They’re fast, consumer-first, and designed to scale.
💡 Connecting The Dots
As longevity medicine struggles to find a profitable, scalable delivery model...gyms may quietly be solving it.
They’re not just spaces to train, they’re evolving into everyday infrastructure for prevention, recovery, and biological optimization.
The future of care may not come from inside the clinic.
It might come from where we already show up.
🐺The Dire Wolf Is Back: What De-Extinction Means for Human Longevity
I had to read it twice.
Colossal Biosciences brought back two Dire Wolves.
Extinct for 10,000 years. Alive again through synthetic biology.
At first glance, it sounds like science fiction. But if we zoom in, there’s something bigger:
🧬 The same biotech tools used to resurrect extinct species are reshaping the future of human health:
Reprogramming aging cells
Regenerating damaged tissue
Extending cellular function and resilience
So, what does this have to do with your future lifespan?
Everything.
While bringing back extinct species and extending human life seem like different goals (reviving species versus extending human healthspan), they rely on the same core technologies: gene editing, cell reprogramming, and genetic engineering.
🔍 De-extinction shows we can take DNA and rebuild life from it.
Now imagine using that same power to reverse aging.
If we can rebuild life from the past, can we rebuild time within the body?
Of course, longevity is tricky.
And yes, it raises big questions:
If we can rebuild life... what risks do we unleash?
But also:
If we get it right, we’re not just adding years.
We’re rewriting what life can be.💭 ✨
Must Reads + Listens
🎙️ Podcast: Optimizing Human Health
Dr. Fady Hannah-Shmouni on Personalized Medicine and Longevity
In this deep conversation at the Mizter Rad Show, Fady shares why the future of healthcare is proactive, personalized, and predictive. This model aims to prevent disease altogether and optimize you before problems emerge.
“We can decelerate aging. We can create healthy, optimized humans.”
→ Your biology will become a digital twin, constantly monitored and optimized
→ Quantum medicine, multi-omics, organoids, stem cells. All of it is real, now
→ Hormonal aging could soon be reversible
🧠 Article: Want to stay young? Peter Diamandis says survive the next 10 years
Peter explains how longevity tech is accelerating, and that the key is just staying healthy long enough to benefit.
“There will be a point where, for every year you’re alive, science adds more than a year to your life.”
→ We may be hitting "longevity escape velocity"
→ Most powerful (and free) intervention? Mindset.
→ Epigenetic reprogramming and cellular repair—is coming fast.
→ $157M XPRIZE is now underway to reverse aging by 2030
💡 Apply to the XPRIZE Longevity Investor Summit →
If you made it this far, that says a lot. You’re probably one of the people building, investing, or thinking ahead, and that’s who this is for.
Thanks for following along.
See you in the next one.